Measuring brain age with EEG and BNA™ could lead to a proactive and scalable approach to early screening for Alzheimer’s patients
KENMORE, N.Y., Jan. 14, 2025 — Firefly Neuroscience, Inc. (“Firefly” or the “Company”) (NASDAQ: AIFF), an Artificial Intelligence (“AI”) company developing innovative solutions that improve brain health outcomes for patients with neurological and mental disorders, today announced the advancement of research to assess a patient’s brain age – an estimation of the biological age of a person’s brain – via its FDA-cleared BNA™ technology platform.
Gil Issachar, Chief Technology Officer of Firefly, commented, “I had the opportunity at AD/PD 2024 to unveil data to an esteemed audience of researchers and clinicians that demonstrated the ability of our groundbreaking BNA™ system, which harnesses Resting EEG and Cognitive EEG (ERP) data, to assess patients’ brain age. To my knowledge, this marks the first instance where cognitive data measured by ERP has been successfully utilized by any technology platform for assessing biological brain age. This innovative approach has the potential to illuminate various facets of human brain aging. BNA™ data assessment, for example, is capable of finding a significant disparity between brain age and chronological age, which could serve as a valuable risk factor for dementia. By being able to measure brain age with EEG, we are potentially paving the way for a proactive and scalable approach to early screening and monitoring for Alzheimer’s patients.”
Greg Lipschitz, Executive Chairman of Firefly, said, “This breakthrough underscores our commitment to pushing the boundaries of innovation in brain health, ultimately with the aim of making a meaningful impact on patients’ lives. I’m incredibly proud of our team for their dedication and ingenuity in bringing this vision to fruition.”
About Firefly
Firefly (NASDAQ: AIFF) is an Artificial Intelligence (“AI”) company developing innovative solutions that improve brain health outcomes for patients with neurological and mental disorders. Firefly’s FDA-510(k) cleared Brain Network Analytics (BNA™) technology revolutionizes diagnostic and treatment monitoring methods for conditions such as depression, dementia, anxiety disorders, concussions, and ADHD. Over the past 15 years, Firefly has built a comprehensive database of brain wave tests, securing patent protection, and achieving FDA clearance. The Company is now launching BNA™ commercially, targeting pharmaceutical companies engaged in drug research and clinical trials, as well as medical practitioners for clinical use.
Brain Network Analytics was developed using artificial intelligence and machine learning on Firefly’s extensive proprietary database of standardized, high-definition longitudinal electroencephalograms (EEGs) of over 17,000 patients representing twelve disorders, as well as clinically normal patients. BNA™, in conjunction with an FDA-cleared EEG system, can provide clinicians with comprehensive insights into brain function. These insights can enhance a clinician’s ability to accurately diagnose mental and cognitive disorders and to evaluate what therapy and/or drug is best suited to optimize a patient’s outcome.